I use restic with resticprofiles (one config file), notifications via (self hosted) ntfy.sh and wasabi as backend. Been very happy, runs reliably and has all the features of a modern backup solution, especially like the option to mount backups as if it were a filesystem with snapshots as folders, makes finding that one file easy without having to recover)

I am using Autosync to sync Obsidian between my mobile, a laptop and a tablet with the central point being Nextcloud. Running without any problems for ca. 3 months.